Tobacco has a negative effect on almost every organ of the body. According to the U.S. Department of Health & Human Services, tobacco use is the leading preventable cause of death in the United States, resulting in more than 443,000 deaths each year. Worldwide, recent studies have shown that tobacco is responsible for about 6 million deaths each year.
In March 2012, the U.S. Department of Health & Human Services reported that, from 1975 to 2000, nearly 800,000 deaths from lung cancer in the United States were prevented due to declines in smoking as a result of tobacco control programs and policies. This data was presented in the Journal of the National Cancer Institute (NCI) and the research was funded by the NCI.
According to the U.S. Centers for Disease Control and Prevention (CDC), the overall rate of cigarette smoking in adults over the age of 18 in the United States dropped from 20.9 percent in 2005 to 17.8 percent in 2013—the lowest rate since record keeping began in 1965. This report, published in the Morbidity and Mortality Weekly Report (MMWR) on November 26, 2014, also indicated that the number of cigarette smokers in the United States fell from 45.1 million in 2005 to 42.1 million in 2013.